The story centers around a timid orphan named Mizumura Shinta who goes to a missionary school in Tokyo. His seemingly normal life changes when a beautiful half-human Romanian girl named Lilith suddenly transfers into his school. Mizumura discovers that he is actually a vampire hunter and the successor of the Romuald lineage. (Source: ANN)

Yukiya Ayase is a gentle, kind hearted, and innocent university student. The only relative he has left, his cousin Tetsuo, betrays Ayase by selling him to the highest bidder in an auction with hopes of making an enormous profit to be able to pay off his debts. Somuku Kanou, a bad-tempered (though very rich) loan shark, comes to Ayase's rescue and buys Ayase for an impressive 1.2 billion. Kanou apparently knows Ayase from something that happened between them in the past, but Ayase cannot remember who Kanou is nor does he understand why he "saved" him. In a desperate effort to keep Ayase close to him, Kanou demands the debt be repaid in full and suggests the perfect way to do it: by selling his body to Kanou for 500,000 each time. Ayase is horrified in the beginning, but something soon begins to grow between them that can't be bought for any price. (Source: ANN)

Kyou no Go no Ni revolves around Sato Ryota, a 5th grader in an elementary school. He is a bright and active boy but always manages to get in to a bit of ecchi trouble with his female classmates.

A short 5-minute special included in the "「Kyou no Go no Ni」 Collectable BOX" Limited Edition DVD released on January 30, 2008.